The ketogenic diet is a low-carbohydrate, high-fat diet that has proven benefits for brain health. Research shows that the keto diet helps ease symptoms of some mental health conditions, including depression and bipolar disorder. But no diet, even keto, is one-size-fits all. Dr. Georgia Ede and Dr. Dominic D’Agostino discuss how diet and brain health are connected, how diet and gut health affect brain health, and how a ketogenic or other low-carbohydrate diets can be tailored to people’s specific needs.

Sign Up to Get Your Free Ultimate Guide to Glucose: ⁠⁠https://levels.link/wnl⁠⁠

Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.

🎙 What Georgia Ede, MD & Dominic D’Agostino, PhD, discuss:

(06:51) — Dr. Georgia Ede describes her interest in nutritional science for mental health

(16:45) — Metabolic health is tied to brain health

(23:16) — A ketogenic diet vs medications for mental health

(27:19) — A ketogenic diet can be tailored to prevent side effects

(32:51) — Gut health and mental health are connected

(39:00) — Diet is highly individual

(42:02) —CGM can teach people how foods and diet strategies affect their health

(44:57) — Following a low-carbohydrate diet will generally reduce insulin levels and triglycerides

(47:40) — Some psychiatric symptoms have links to higher C-reactive protein levels

(48:42) — Dr. D’Agostino summarizes one of Dr. Ede’s studies on the ketogenic diet and mental health

(56:59) — A ketogenic diet may also help ease some menopause symptoms

⁠Transcripts & Show notes⁠

🔗 Helpful links:

Watch the conversation: ⁠⁠https://youtu.be/kBjBEjV0vqU⁠

Find us on YouTube: ⁠⁠https://youtube.com/levelshealth?sub_confirmation=1

Not all calories are equal. Tracking your macronutrient intake, using AI capabilities, can help you improve your body composition, facilitate weight loss, and boost exercise performance. The three macronutrients are protein, fat, and carbohydrates, with fiber a subset of carbs. Josh Clemente & Dr. Dominic D'Agostino discuss the new macros-tracking feature in the Levels app, the purpose and importance of each macronutrient, how to use macros-tracking in conjunction with biomarker data to improve health and fitness, and how easy the app’s AI functionality is to use.

Sign Up to Get Your Free Ultimate Guide to Glucose: ⁠⁠⁠⁠⁠https://levels.link/wnl⁠⁠⁠⁠

Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.

🎙 What Josh Clemente & Dominic D'Agostino, PhD, discuss:

(09:03) — The importance of prioritizing protein intake

(17:03) — Why is tracking macros beneficial?

(21:11) — Each macronutrient has a different role in the body

(39:36) — The different functions of macros

(48:32) — Is excess protein a concern?

(54:55) — The problem with excess carbohydrates

(1:00:37) — Tracking macros can help you improve metabolic flexibility

(1:02:41) — The issue with overconsumption of carbohydrates

(1:17:18) — Is fiber a macronutrient?

(1:46:21) — Macros tracking in the Levels app

(1:49:50) — Tracking macros can help improve body composition and performance

Transcripts & Show notes

🔗 Helpful links:

Watch the conversation: https://youtu.be/wg76Q25Ngd4

Find us on YouTube: ⁠⁠⁠⁠⁠https://youtube.com/levelshealth?sub_confirmation=1⁠⁠

Fructose and its byproduct uric acid may play a role in the development of Alzheimer’s, thanks to an evolutionary adaptation hijacked by the modern diet. Fructose can be directly consumed, or the body can convert high-glycemic carbohydrates and other foods to fructose. Fructose suppresses some cognitive functions. Dr. Richard Johnson and Dr. Rob Lustig discuss a new study, of which Johnson was an author, on how fructose may be a potential driver in Alzheimer’s, and they hypothesize about fructose’s potential connection to the development of other conditions.

Sign Up to Get Your Free Ultimate Guide to Glucose: ⁠https://levels.link/wnl⁠

🎙 What Richard Johnson, MD, & Rob Lustig, MD, discuss:

(09:50) — Fructose is the driver of some diseases that are on the rise in kids

(11:53) — Fructose is a driver of obesity and metabolic syndrome

(15:36) — Pharmaceutical treatments for Alzheimer’s disease aren’t as effective as researchers had hoped

(17:32)— The research focus of Alzheimer’s is slowly shifting to understanding insulin resistance in the brain

(20:41) — Is fructose a root cause of Alzheimer’s?

(26:26) — New research suggests fructose induces a foraging response

(28:20) — Fructose inhibits areas of the brain to encourage successful foraging

(46:48) — We need more research on fructose

(1:03:10) —Is fructose a factor in violence?

⁠Transcripts & Show notes⁠

Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.

👋 WHO WE ARE:

Levels helps you see how food affects your health. With real-time, personalized data gathered through biosensors like continuous glucose monitors (CGM), you learn which diet and lifestyle choices improve your metabolic health so you can live a longer, fuller, healthier life.

🔗 LINKS:

Could Alzheimer’s disease be a maladaptation of an evolutionary survival pathway mediated by intracerebral fructose and uric acid metabolism?: ⁠https://www.sciencedirect.com/science/article/abs/pii/S0002916523000047?dgcid=author⁠

Subscribe here on YouTube: ⁠https://youtube.com/levelshealth?sub_confirmation=1⁠

Gastrointestinal health, metabolic health, and fertility are all linked. The gut microbiome impacts other microbiomes in the body, which can then impact the ability to conceive. Our gut microbiomes are becoming less diverse through modern farming practices and the consumption of processed foods. Dr. Robin Rose and Ben Grynol discuss how gut microbiome testing can determine underlying factors of gastrointestinal distress and the lifestyle changes that can help address symptoms and even aid fertility.

Sign Up to Get Your Free Ultimate Guide to Glucose: ⁠https://levels.link/wnl⁠

🎙 What Robin Rose, MD, & Ben Grynol discuss:

(08:05) — Gastrointestinal issues are associated with metabolic health issues

(08:56) — Many people lack gut microbiome diversity

(15:24) — Infertility in some people has links to the gut microbiome

(30:56) — PCOS and gut dysbiosis share a connection that’s still being researched

(32:26) — Restoring gut and metabolic health may help alleviate PCOS symptoms

(34:44) — Metagenomic testing assesses gut health

(39:47) — Gut health often requires balanced macronutrient intake

(49:14) — Regenerative farming practices could help us get more quality nutrients

(54:57) — Eliminating dairy and gluten may ease gastrointestinal symptoms

(56:29) — Sleep quality and quantity also inform gut health

⁠Transcript & Show Notes⁠

Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.

🔗 Helpful links:

Watch the conversation: ⁠https://youtu.be/SpW9znY3fkI⁠

Find us on YouTube: ⁠https://youtube.com/levelshealth?sub_confirmation=1⁠

High-carbohydrate diets and carbohydrate loading have been long-standing tenets of athletic training and competition, but newer research indicates a low-carbohydrate diet may be more beneficial for performance and overall health. Professor Tim Noakes and Josh Clemente discuss how a fat-adapted body can rely on fat as a fuel source at all exercise intensity levels, rather than burning mostly carbohydrates, and how such adaptation and dietary focus may reduce one’s risk of prediabetes and Type 2 diabetes.

Sign Up to Get Your Free Ultimate Guide to Glucose: ⁠https://levels.link/wnl⁠

Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.

🎙 What Tim Noakes, MD, PhD, & Josh Clemente discuss:

(04:28) — Dr. Tim Noakes explains his career trajectory

(19:04) — An adapted body can rely on fat for all exercise intensities

(22:30) — The body will never get to a state of no glucose circulation

(23:28) — A delicate balance of macronutrients is likely necessary

(29:11) — Before the high-carbohydrate craze, elite athletes were fat adapted

(33:46) — Fat oxidation in muscle may have a protective effect against Type 2 diabetes

(36:39) — Exercise does not cancel out the risk for metabolic disease if diet isn’t accounted for

(47:25) — The body can cope with fasting

(54:32) — The high-carb training trend has been perpetuated by the carbohydrate industry

⁠Transcripts & Show notes⁠

🔗 Helpful links:

Find us on YouTube: ⁠https://youtube.com/levelshealth?sub_confirmation=1⁠

Your sleep routine is one of the most important aspects of your metabolic health. Look for multiple new shows per week on A Whole New Level, where we have in-depth conversations about metabolic health and how the Levels startup team builds a wellness movement from the ground up in the health and wellness tech industry.

Sign Up to Get Your Free Ultimate Guide to Glucose: ⁠https://levels.link/wnl⁠

Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.

🎙 What Ben Grynol and Mike Haney discuss:

(02:36) - A study about sleep and metabolic health

(03:26) - The benefits of sleep for metabolic health

(05:24) - Sleeping at home

(05:24) - Standardized meals

(07:20) - How glucose levels affect sleep quality and duration

(12:50) - What you eat matters

(14:37) - Sleep quality and glucose

(18:06) - Sleep is the most important thing you control

(18:55) - Don’t sacrifice sleep

(20:08) - The importance of consistency

(25:29) - Compounding effects work both ways

⁠Transcripts and Show Notes⁠

🔗 Helpful links:

How does sleep affect blood sugar?: ⁠https://levelshealth.com/blog/how-sleep-impacts-metabolic-health-glucose-levels-cgm⁠

Find us on YouTube: ⁠https://youtube.com/levelshealth?sub_confirmation=1⁠

Stable glucose levels are a foundation of feeling and looking your best at any age. When glucose levels are more erratic—with spikes and crashes—cravings, weight gain, low energy, health issues, and more can ensue. Jessie Inchauspé and Dr. Casey Means, thought leaders on the topic of blood sugar, discuss simple hacks for keeping glucose levels more stable without resorting to restrictive diets, and they share why stable levels inform health.

Sign Up to Get Your Free Ultimate Guide to Glucose: ⁠⁠⁠⁠https://levels.link/wnl⁠⁠⁠

Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.

🎙 What Jessie Inchauspé & Casey Means, MD, discuss:

(12:59) — Are type 2 diabetes and obesity genetic, dictated by lifestyle factors, or both?

(15:53) — Hacks for keeping blood sugar more stable

(24:22) — People want to be healthy, but the food industry complicates matters

(28:29) — Nutritional choices can impact mental health

(35:56) — The premise behind Inchauspé’s ‘Glucose Goddess Method’

(39:59) — Tracking biomarkers provides insight to your metabolic health

(42:08) — A siloed approach to healthcare misses the big picture

(45:06) — Can supplements really help with metabolic health?

(57:37) — We need systemic change in the food industry

(1:05:52) — The science behind food cravings

⁠⁠Transcripts & Show notes⁠⁠⁠⁠

🔗 Helpful links:

Find us on YouTube: ⁠⁠⁠⁠https://youtube.com/levelshealth?sub_confirmation=1⁠⁠

Jessie Inchauspé on Instagram: https://www.instagram.com/glucosegoddess/

Jessie Inchauspé: https://www.antispike.com

Casey Means, MD: https://www.caseymeans.com/goodenergy

Good Energy: The Surprising Connection Between Metabolism and Limitless Health: https://www.caseymeans.com/goodenergy

Can a holistic protocol address the root cause of autoimmune diseases like multiple sclerosis (MS)? We explore how metabolic health is tightly linked to autoimmune diseases and how understanding blood sugar levels and insulin sensitivity is key. Dr. Terry Wahls developed The Wahls Protocol, which helped Dr. Wahls reverse her disease process and helped her get back on her feet. The Wahls Protocol is one of the most influential lifestyle programs that helps people address their autoimmune diseases. Look for multiple new shows per week on A Whole New Level, where we have in-depth conversations about metabolic health and how the Levels startup team builds a wellness movement from the ground up in the health and wellness tech industry.

Sign Up to Get Your Free Ultimate Guide to Glucose: ⁠⁠⁠https://levels.link/wnl⁠⁠

Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.

🎙 What Dr. Terry Wahls and Dr. Casey Means discuss:

(03:46) - A new framework for thinking about autoimmune disease

(06:52) - A supplement cocktail

(13:27) - The creation of health

(15:56) - Humans are metabolically complex

(17:50) What is mitochondrial dysfunction?

(28:46) - The connection between type-1 diabetes and mitochondrial dysfunction

(37:30) - Addressing the root cause of autoimmune issues

(43:35) - How to support mitochondrial health

(45:01) - Improving metabolic health can improve autoimmune disease

⁠Transcripts & Show notes⁠⁠⁠

🔗 Helpful links:

Find us on YouTube: ⁠⁠⁠https://youtube.com/levelshealth?sub_confirmation=1⁠⁠

Traditional soft drinks, juice boxes, and energy and sports drinks are loaded with high fructose corn syrup, an ingredient also found in many processed foods. The body processes fructose differently than other sugars, and fructose can lead to weight gain by encouraging the body to store energy. Dr. Richard Johnson and Dr. Dominic D’Agostino discuss the issues with fructose, sucralose (found in PRIME energy drinks), and other artificial sweeteners. They explore how fructose can drive food cravings and overeating, its potential role as an Alzheimer’s contributor, and the benefits of a different sugar that might promote the release of GLP-1, the hormone that Ozempic and Wegovy help increase.

Sign Up to Get Your Free Ultimate Guide to Glucose: ⁠⁠https://levels.link/wnl⁠⁠

Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.

🎙 What Richard Johnson, MD, & Dominic D’Agostino, PhD, discuss:

(1:59) — Richard Johnson, MD, is a prolific researcher regarding sugar’s effects

(6:38) — Soft drinks are a major source of added sugar, which has negative effects on metabolic health

(8:31) — Fructose lowers energy in the body, driving hunger

(14:16) — Fructose can drive insulin resistance and increase fat

(21:44) — A small amount of fructose can be beneficial to the body

(29:11) — Fructose consumption may be a culprit of Alzheimer’s disease

(48:21) — Low-calorie sugars can still make you crave more sugar

(53:59) — A low-calorie sugar called allulose has potential health benefits

(55:59) — Allulose may stimulate GLP-1

(59:39) — A low-carb diet helps reduce sugar cravings

⁠Transcripts & Show notes⁠⁠

🔗 Helpful links:

Find us on YouTube: ⁠⁠https://youtube.com/levelshealth?sub_confirmation=1⁠⁠

Watch the full conversation: ⁠https://youtu.be/AMgBxyJvtx0

What are the unique metabolic health experiences of South Asian and Black communities? In this candid conversation between serial entrepreneur and health and wellness investor Dhru Purohit and content creator and metabolism mentor Austin McGuffie, they discuss how metabolic health affects their respective communities.

Sign Up to Get Your Free Ultimate Guide to Glucose: ⁠⁠https://levels.link/wnl

Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.

🎙 What Dhru Purohit & Austin McGuffie discuss:

(18:51) – Live by example

(23:21) – Focus on education first

(24:53) – The benefits of targeted fasting

(26:08) – Dying from excess

(30:03) – It all comes back to lifestyle

(34:42) – Talk to people who are on the fence

(35:57) – The societal split

(36:52) – Why we need targeted solutions

(38:45) – The add-in method

(52:09) – Health happens in community

⁠Transcripts & Show Notes

🔗 Helpful links:

Find us on YouTube: ⁠⁠⁠https://youtube.com/levelshealth?sub_confirmation=1⁠⁠