This episode is brought to you by Rupa Health, Pendulum, Mitopure, and Thrive Market. The world is facing several big challenges today—the climate crisis, food insecurity, racial injustice, the rise of AI, and insufficient access to healthcare, to name just a few.  Today on The Doctor’s Farmacy, I am excited to talk to Dr. Rajiv Shah about how large-scale change really happens, the success and lessons he has learned throughout his career, and why we need big bets—large, bold actions—in order to solve the world’s greatest challenges. Dr. Rajiv Shah serves as president of the Rockefeller Foundation, a global institution with a mission to promote the well-being of humanity around the world. With a century-long track record of leveraging science, technology, and innovation, The Foundation is pioneering new ways to enable individuals, families, and communities to flourish. Dr. Shah is a graduate of the University of Michigan, the University of Pennsylvania School of Medicine, and the Wharton School. He has received several honorary degrees, the Secretary of State’s Distinguished Service Award, and the US Global Leadership Award. He is married to Shivam Mallick Shah, and they have three children. This episode is brought to you by Rupa Health, Pendulum, Mitopure, and Thrive Market. Access more than 3,000 specialty lab tests with Rupa Health. You can check out a free, live demo with a Q&A or create an account at RupaHealth.com today. Get 20% off your first month of your Pendulum subscription with code HYMAN. Head to Pendulumlife.com to check it out. Support the growth of new, healthy mitochondria and get 10% off of Mitopure. Head to timelinenutrition.com/drhyman and use code DRHYMAN10 at checkout. Head over to thrivemarket.com/Hyman today to receive 30% off your first order and a free gift of up to $60. Here are more details from our interview (audio version / Apple Subscriber version): How Rajiv was inspired by Nelson Mandela in his youth (5:25 / 3:41) The first crisis Rajiv dealt with as the head of USAID (9:05 / 7:21) Tackling the chronic disease epidemic with food as medicine (14:54 / 13:09) Addressing rising obesity rates in America (32:31 / 27:52) The importance of believing change is possible (42:33 / 37:54) What makes the standard American diet so unhealthy? (48:42 /  Investing in weight-loss drugs vs quality food (49:26 / 44:03) The importance of finding the right partners to make meaningful change (52:13 / 47:35) Finding happiness through service to others (56:02 / 51:25) Rajiv’s next big bets (1:04:14 / 59:40) Get a copy of Big Bets: How Large-Scale Change Really Happens. Learn more about your ad choices. Visit megaphone.fm/adchoices