This episode is brought to you by Rupa Health, BiOptimizers, Mitopure, and AquaTru. ⁣⁣NAD has been popping up everywhere, and for good reason. It’s a fundamental driver of our health and longevity, and we’re now learning how boosting NAD levels might offset and improve the effects of aging.  On today’s episode, I’m excited to talk to Dr. Andrew Salzman all about NAD—how it is a key component involved in mitochondrial production, and is a critical substrate for several enzymes, including sirtuins, which play key roles in healthy aging, weight management, metabolic syndrome, and metabolism. Dr. Salzman is a physician, inventor, professor, and biomedical entrepreneur. Dr. Salzman received his medical degree from Harvard University and has spent decades in drug discovery and development, raising over $165M in NIH grants for research. In addition to 50 patents, Dr. Salzman is credited with a breakthrough discovery in cellular DNA repair, which led to the world's first clinical application for successfully treating breast cancer caused by mutations in BRCA1 and BRCA2 genes. Millions of patients are benefiting from discoveries by Dr. Salzman in areas including mitochondrial health, gastrointestinal microbiota, damage caused by inflammation and oxidative stress to human cells and DNA, autoimmune disease, and cancer. This episode is brought to you by Rupa Health, BiOptimizers, Mitopure, and AquaTru. Rupa Health is a place where Functional Medicine practitioners can access more than 3,000 specialty lab tests from over 35 labs. You can check out a free, live demo with a Q&A or create an account a RupaHealth.com. BiOptimizers is offering my listeners 10% off Sleep Breakthrough. If you buy two or more you’ll get a free bottle of Magnesium Breakthrough. This is a limited-time offer. Go to sleepbreakthrough.com/hyman and use the code hyman10.  Get 10% off Mitopure at timelinenutrition.com/drhyman and use code DRHYMAN10 at checkout. Right now, my podcast listeners can access the AquaTru water filter for as low as $249. That’s $100 off the normal price. All you have to do is go to drhyman.com/filter, and you can get this special, exclusive price. Here are more details from our interview (audio version / Apple Subscriber version): How NAD helps us produce energy (5:00 / 3:04)  The science behind how NAD impacts health and longevity (10:08 / 8:15)  The role NAD plays in maintaining health (16:27 / 13:26)  NAD’s multiple functions (23:46 / 21:18)  Preserving NAD levels (30:34 / 27:47)  Where NAD is made in the body (34:53 / 30:35)   How NAD benefits sleep (41:17 / 37:04)  Do NMN and NAD cause cancer? (47:12 / 42:57)  Research on NMN in humans (50:23 / 46:07)  The difference between NMN and NR (1:00:54 / 51:55)  Learn more about Wonderfeel Youngr NMN. Learn more about your ad choices. Visit megaphone.fm/adchoices