Today’s Talmud page, Yevamot 101, tells a story about a wayward son as a way of asking a major theological question about doubt, certainty, and their role in the believer's life. The late Rabbi Lord Jonathan Sacks addressed this question in one of his memorable talks, and we are privileged to share his insights on the value of radical uncertainty. What is the secret and often misunderstood essence of faith? Listen and find out. The audio of Rabbi Lord Jonathan Sacks was originally found on The Rabbi Sacks Legacy Trust website. Like the show? Send us a note at takeone@tabletmag.com. Follow us on Twitter at @takeonedafyomi and join the conversation in the Take One Facebook group. Take One is a Tablet Studios production. The show is hosted by Liel Leibovitz, and is produced and edited by Darone Ruskay and Quinn Waller. Our team also includes Stephanie Butnick, Josh Kross, Mark Oppenheimer, Sara Fredman Aeder, Robert Scaramuccia, and Tanya Singer.  Check out all of Tablet’s podcasts at tabletmag.com/podcasts.