In the 1980s Mimi Pond was a cartoonist and illustrator for such publications as the National Lampoon, the Village Voice, The New York Times, Seventeen Magazine, Adweek, and too many more to mention, as well as writing and illustrating five humor books, beginning with the national best-seller, The Valley Girls’ Guide to Life. She wrote the first episode of the animated series, The Simpsons, and has written for other television shows as well.

With her husband, the artist Wayne White, she moved to Los Angeles in 1990 and since then has continued to write and to draw cartoons for numerous national magazines.

In 2014, her graphic novel, Over Easy, a fictionalized account of her post-art school waitressing career in Oakland, California in the late 1970s, was published by Drawn Quarterly and has been on the New York Times Best Seller List.