Tens of thousands of Londoners developed painful, apple-sized, pus-filled boils before dying from the dreadful disease within days. But just as the ordeal of the Black Death seemed to be subsiding, the Great Fire struck the city. But did the conflagration actually save the lives of thousands? In this scorcher of a show, we go in search of the cause of the plague, explore the origins of the Great Fire, and ask whether history might repeat itself? Like this podcast? Please help us by supporting the Naked Scientists