Tilda Swinton stars as Marianne Lane, a Bowie-esque,world renown rock star who is on vacation with Paul, her documentarian boyfriend of six years, on Pantelleria, a small, secluded Mediterranean island off between the coasts of Sicily and Tunisia. Marianne is there for some R&R from her most recent tour, in recovery from surgery on her throat that she is hoping will be successful so that she can resume her singing career. Their "alone time" is soon ended by the arrival of her rambunctious previous lover and legendary music producer Harry Hawkes, along with the grown daughter Harry has only recently discovered, Penelope, ostensibly as a friendly visit, but it soon becomes apparent that they're seeking to cause division in the relationship for their own ends.