Dr. Katherine MacLean is a neuroscientist, writer, research scientist, mother, and adventure-seeker. Dr. Maclean thought she would study anthropology, religion, or pre-Med when she first started undergraduate school. She had many interests including genetics, spirituality, and the brain. She recalls “I took an anthropology of religion course, and that’s when I first learned about Shamanic and spiritual ceremonies that could trigger changes in the brain that created visions that created the experience of real-life entities.” At the time, she also took psychology courses and learned there was a rhesus macaque lab in the basement. She wanted to find out what those monkeys were doing in the basement so with the help of her undergrad mentor, Yale Cohen, she was able to corral all of her disparate interests and combine them with her passion to forge a new research path that combined her work on mindfulness research while earning her doctorate at UC-Davis and her psilocybin research at Johns Hopkins University where she completed her postdoctoral fellowship in psychopharmacology. In this podcast interview, Dr. MacLean brings us back to her undergraduate and graduate experiences and shares the critical events and people that led her to obtain her Bachelor of Arts in Psychology and Neuroscience and attend UC-Davis for her PhD in Research Psychology as well as attending Johns Hopkins University for her postdoctoral fellowship in psychopharmacology. She shares her experience visiting graduate schools and how she mentioned her interest in studying psychedelics “just to see how they would respond.” At the time, serious research on psychedelics was not happening so Dr. MacLean combined her interests and passion to establish a legitimate line of groundbreaking research studying the effects of mindfulness meditation and psychedelics on cognitive performance, emotional well-being, spirituality, and brain function. Her research suggests that psychedelic medicines can enhance openness to new experiences and promote mental health and emotional well-being throughout the life span. Dr. MacLean co-founded and directed the first center for psychedelic training and education in New York, was featured in the New Yorker article entitled “The Trip Treatment by Michael Pollan, and her TED Talks have been viewed nearly fifty thousand times. She was one of the lead researchers on the Shamatha Project, which was a groundbreaking study of the effects of intensive meditation on psychological and brain function. When she was a research follow and faculty member at Johns Hopkins, she apprenticed with and was supervised by two of the world’s top psychedelic therapists – Bill Richards, PhD, and Mary Cosimano, LSW – learning how to effectively and safely support people before, during, and after high-dose psychedelic experiences. When reflecting on your journey and her professional career, Dr. MacLean shares practical advice for those “climbing the ladder of success.” She states, “I might have been very happy as a tenure track faculty member at Johns Hopkins. But, the thing that I want to impress upon young psychology students is something that a medical doctor told me when I was deciding whether to leave Hopkins, ‘sometimes as you’re climbing the ladder of success, you get to the top and realize it’s on the wrong wall and you have to get all the way back down and put the ladder up on a different wall and start from scratch.’” Dr. MacLean spent the last two decades studying the effects of mindfulness meditation and psychedelics on cognitive performance, emotional well-being, spirituality, and brain function. Her professional journey takes an unexpected detour following the death of her sister from cancer. She left her faculty position and decided to travel the world. In her new book, Midnight Water: A Psychedelic Memoir, she shares her story of grief and redemption. During our discussion she shares more about her book, why she wrote it,