In this episode of On The Margin Mike is joined by Ryan Selkis Co-Founder & CEO at Messari. Having released the 150+ page 'Crypto Theses for 2022' report, we invited Ryan to the show to discuss the most important trends to look out for in the industry. Mike & Ryan discuss the Layer-1 wars, venture capital investment in crypto, NFTs 100x potential, regulation for crypto & DAOs, Ryan's market outlook for 2022 & so much more. Link to the full report - https://messari.io/crypto-theses-for-2022 -- Ledger: This episode is brought to you by Ledger, your secure gateway to buy, exchange and grow your crypto. Combine a Ledger hardware wallet with the Ledger Live app to access all your favorite crypto services & DApps from one place. All that with the best security. Visit https://onthemargin.link/ledger and make your crypto journey easier and safer. -- Coinbase Prime: On The Margin is supported by Coinbase Prime, an integrated solution that provides advanced multi-venue trading, custody, and prime services for institutions. For more information go to https://onthemargin.link/coinbase -- OurCrowd: Join the fastest growing venture capital investment community, at https://www.ourcrowd.com/otm --- If you like this episode be sure to subscribe to our newsletter at https://blockworks.co/newsletter On The Margin is brought to you by Blockworks, a financial media brand delivering breaking news and premium insights about digital assets to millions of investors. For more content like On the Margin, visit http://blockworks.co/podcasts.