Derek Zoolander is back, the eternally daft and narcissistic male supermodel, now retired and reclusive, who has been persuaded by a 'fashion police' agent working for Interpol, Valentina Valencia, to help find the killers of a growing list of celebrities who've struck what appears to be Zoolander's signature "Blue Steel" pose for an Instagram selfie done right before their moment of death.  His wife deceased and his child taken away by protective services, Derek has a chance of getting Derek Jr. back by coming out of exile in the mountainous wilderness of northern New Jersey (one of the film's feeble jokes) and assisting with the investigation in Rome, with former rival-turned-friend Hansel in tow.  The clues lead them back to Zoolander's incarcerated megalomaniacal nemesis Mugatu in a plot involving the search for the Fountain of Youth.