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Submit ReviewThe fall Covid-19 booster campaign will be upon us soon and how well the new Omicron-specific boosters will work may depend on a phenomenon called “original antigenic sin.” Since people have been infected, vaccinated, and boosted, people’s immune systems are on different playing fields and your first exposure may play a bigger part in future immune responses. Carolyn Johnson, science reporter at the Washington Post, joins us for what to know.
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