Podknife - TWiV 815: MIS-C with Moshe Arditi and Ivet Bahar by This Week in Virology

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TWiV 815: MIS-C with Moshe Arditi and Ivet Bahar

Podcast |: This Week in Virology
Publisher |: American Society for Microbiology
Media Type |: audio
Podknife tags |: Health,; Roundtable,; Science & Medicine
Categories Via RSS |: Medicine,; Science & Medicine
Publication Date |: Oct 10, 2021
Episode Duration |: 02:02:51

Moshe and Ivet join TWiV to discuss their finding that MIS-C is a consequence of a superantigen in the spike protein of SARS-CoV-2 that causes activation of a skewed population of T cell receptor bearing lymphocytes, leading to hyperinflammation.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condi t and Kathy Spindler

Guests: sinai.edu/research/labs/arditi.html">Moshe Arditi and Ivet Behar

Subscribe (free): iTunes, Google Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

MIS-C in US children (NEJM)
Superantigen in spike and T cell skewing in MIS-C (PNAS)
MIS-C mimics toxic shock syndrome (J Allergy Clin Immunol)
Antibody against bacterial superantigen blocks SARS-CoV-2 entry (Structure)
Autoimmune signature of MIS-C in children (J Clin Invest)
HLA1 associated T cell expansion in MIS-C (J Clin Invest)
Passing of Bill Wold (one, two)
Letters read on TWiV 815
Timestamps by Jolene. Thanks!

Weekly Picks

Dickson – Mel Brooks Kathy – Dickson-Despommier.html"> Dickson’s art show at Fordham Rich – Saildrone captures footage from inside Hurricane Sam Vincent – A Shot to Save the World: The Inside Story of the Life-or-Death Race for a COVID-19 Vaccine by Gregory Zuckerman

Listener Picks

Kathryn – Project Drawdown and the book Charles – Arrowsmith by Sinclair Lewis

Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv

TWiV is a weekly netcast about viruses - the kind that make you sick. Brought to you by four university professors and a science writer.

Hosts: Vincent Racaniello, Dickson Despommier, Rich Condi t and Kathy Spindler

Guests: sinai.edu/research/labs/arditi.html">Moshe Arditi and Ivet Behar

Subscribe (free): iTunes, Google Podcasts, RSS, email

Become a patron of TWiV!

Links for this episode

MIS-C in US children (NEJM)
Superantigen in spike and T cell skewing in MIS-C (PNAS)
MIS-C mimics toxic shock syndrome (J Allergy Clin Immunol)
Antibody against bacterial superantigen blocks SARS-CoV-2 entry (Structure)
Autoimmune signature of MIS-C in children (J Clin Invest)
HLA1 associated T cell expansion in MIS-C (J Clin Invest)
Passing of Bill Wold (one, two)
Letters read on TWiV 815
Timestamps by Jolene. Thanks!

Weekly Picks

Dickson – Mel Brooks Kathy – Dickson-Despommier.html"> Dickson’s art show at Fordham Rich – Saildrone captures footage from inside Hurricane Sam Vincent – A Shot to Save the World: The Inside Story of the Life-or-Death Race for a COVID-19 Vaccine by Gregory Zuckerman

Listener Picks

Kathryn – Project Drawdown and the book Charles – Arrowsmith by Sinclair Lewis

Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv

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