Drugs, Episode 1 of 4. Quinine, the alkaline derived from the bark of the quina-quina tree, would prove the most effective treatment for malarial fever and infection in human history. In the decades after the bark of the tree was exported to Europe, every state with imperialist aspirations wanted access to quinine. The Spanish Crown, recognizing quina bark for its power and lucrativeness, monopolized the harvest and export of the medicament. By the beginning of the 19th century, the imperialist aspirations of Europeans required an effective malaria treatment. The quest for quinine led to a robust smuggling ring empowered by the Age of Revolutions, Italian social welfare, and the invention of the British Empire’s cocktail of choice. Quinine’s role in reshaping the world is immeasurable… but we’re going to give it the old college try! For the complete transcript and full bibliography, visit digpodcast.org Select Bibliography Lucile H. Brockway, Science and Colonial Expansion: The Role of the British Royal Botanic Gardens (Yale University Press, 2002) Matthew Crawford, The Andean Wonder Drug: Cinchona Bark and Imperial Science in the Spanish Atlantic, 1630-1800, (University of Pittsburgh Press, 2016) Stefanie Gänger, A Singular Remedy: Cinchona Across the Atlantic World, 1751–1820 (Cambridge University Press, 2020) Daniel R. Headrick, The Tools of Empire: Technology and European Imperialism in the Nineteenth Century, (Oxford University Press, 1981). Andreas-Holger Maehle, Drugs on Trial: Experimental Pharmacology and Therapeutic Innovation in the Eighteenth Century (Rodopi, 1999) Clements Markham,Travels in Peru and India, (London: John Murray, 1862). Digitized by Project Gutenberg. Frank M. Snowden, The Conquest of Malaria: Italy, 1900-1962, (Yale University Press, 2006). Learn more about your ad choices. Visit podcastchoices.com/adchoices

Drugs, Episode 1 of 4. Quinine, the alkaline derived from the bark of the quina-quina tree, would prove the most effective treatment for malarial fever and infection in human history. In the decades after the bark of the tree was exported to Europe, every state with imperialist aspirations wanted access to quinine. The Spanish Crown, recognizing quina bark for its power and lucrativeness, monopolized the harvest and export of the medicament. By the beginning of the 19th century, the imperialist aspirations of Europeans required an effective malaria treatment. The quest for quinine led to a robust smuggling ring empowered by the Age of Revolutions, Italian social welfare, and the invention of the British Empire’s cocktail of choice. Quinine’s role in reshaping the world is immeasurable… but we’re going to give it the old college try! For the complete transcript and full bibliography, visit digpodcast.org Select Bibliography Lucile H. Brockway, Science and Colonial Expansion: The Role of the British Royal Botanic Gardens (Yale University Press, 2002) Matthew Crawford, The Andean Wonder Drug: Cinchona Bark and Imperial Science in the Spanish Atlantic, 1630-1800, (University of Pittsburgh Press, 2016) Stefanie Gänger, A Singular Remedy: Cinchona Across the Atlantic World, 1751–1820 (Cambridge University Press, 2020) Daniel R. Headrick, The Tools of Empire: Technology and European Imperialism in the Nineteenth Century, (Oxford University Press, 1981). Andreas-Holger Maehle, Drugs on Trial: Experimental Pharmacology and Therapeutic Innovation in the Eighteenth Century (Rodopi, 1999) Clements Markham,Travels in Peru and India, (London: John Murray, 1862). Digitized by Project Gutenberg. Frank M. Snowden, The Conquest of Malaria: Italy, 1900-1962, (Yale University Press, 2006). Learn more about your ad choices. Visit podcastchoices.com/adchoices