Sal Gentile was born in the Bronx, New York. He learned about business from a very young age. His parents operated a small business, a fish market that had been passed down for three generations. He went through the conventional education system, got a degree, and started working for major corporations. Later on, he found his place in the healthcare sector, providing valuable insurance to consumers after the passage of the Affordable Care Act (ACA). His venture Friday Health Plans has raised funding from top-tier investors like Vestar Capital Partners, Leadenhall Capital Partners, Peloton Equity, and The Colorado Impact Fund.