A new variant of SARS-CoV-2 is making its way around the world; in the U.S., it has been found in at least three states: California, Colorado, and New York. Joe Osmundson, an assistant professor of biology at New York University, speaks with the New Yorker staff writer Carolyn Kormann about why this new strain is particularly concerning. It has twenty-three mutations—far more than scientists would expect an RNA virus to have—which makes it at least fifty per cent more contagious than the original virus. The response, Osmundson says, should be to double down on reducing transmission by encouraging a culture of caution. Mask wearing, he warns, might be with us for a long time. Osmundson came of age as a gay man during the AIDS crisis, and he compares our pressing need for social distancing to the cultural change that took place during that era. “It was not a joy, growing up, to worry about H.I.V. every time I had sex, and to feel like if I don’t wear a condom, I might die,” he tells Kormann. “And yet that was part of how we cared for each other. It is a way to care.” Plus, a music editor and writer picks some favorites from a very specific genre: posthumous rap albums.