Today you’ll learn about the development of a potential new Covid vaccine in the form of a nasal spray, how your circadian rhythm affects how intensely you feel pain, and how the old saying that you need 8 glasses of water a day could be a myth. 

Pain Worse at Night 

• “Why pain feels worse at night” by Allison Whitten
  • https://arstechnica.com/science/2022/09/why-pain-feels-worse-at-night/
• “Circadian rhythmicity of pain sensitivity in humans” by Inès Daguet, Véronique Raverot, Didier Bouhassira, and Claude Gronfier
  • https://academic.oup.com/brain/article/145/9/3225/6637506?guestAccessKey=e94c8f79-7fca-42ca-98e2-085eb26400c3&login=false

Who Needs Water?  

• “Stop counting cups. There’s an ocean of difference in our water needs” by UNIVERSITY OF WISCONSIN-MADISON
  • https://www.eurekalert.org/news-releases/972344
• “Variation in human water turnover associated with environmental and lifestyle factors” by YOSUKE YAMADA et al.
  • https://www.science.org/doi/10.1126/science.abm8668

Covid Nasal Spray  

• “How nasal-spray vaccines could change the pandemic” by Emily Waltz
  • https://www.nature.com/articles/d41586-022-02824-3
• “Investigational Mucosal COVID Vaccine Protects Against Disease and Transmission” by Sarah Avery
  • https://corporate.dukehealth.org/news/investigational-mucosal-covid-vaccine-protects-against-disease-and-transmission

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Find episode transcripts here: daily-4e53644e.simplecast.com/episodes/pain-worse-at-night-who-needs-water-covid-nasal-spray">https://curiosity-daily-4e53644e.simplecast.com/episodes/pain-worse-at-night-who-needs-water-covid-nasal-spray