Ketlen Vieira and Sean Brady picked up the biggest wins of their careers on Saturday. While they will both take steps forward, how close are they to championship opportunities following UFC Vegas 43? This week, the On To the Next One squad answers those questions, along with where former bantamweight champion Miesha Tate goes from her first loss since making her return to competition. In addition, MMA Fighting's Mike Heck and Alexander K. Lee take a look at what could be next for Taila Santos — following her dominant submission win over Joanne Wood — Rani Yahya, Adrian Yanez, and more. Follow Mike Heck: @MikeHeck_JR Follow Alexander K. Lee: @AlexanderKLee Subscribe: http://goo.gl/dYpsgH Check out our full video catalog: http://goo.gl/u8VvLi Visit our playlists: http://goo.gl/eFhsvM Like MMAF on Facebook: http://goo.gl/uhdg7Z Follow on Twitter: http://goo.gl/nOATUI Read More: http://www.mmafighting.com Learn more about your ad choices. Visit podcastchoices.com/adchoices