As COVID-19 cases surge, U.S. Surgeon General Dr. Vivek Murthy explains why the “next few weeks are going to be tough,” the importance of getting vaccinated despite breakthrough cases and responds to the CDC’s new guidance for asymptomatic individuals. Then, Ralph Macchio discusses the evolution of his “The Karate Kid” and “Cobra Kai” character Daniel LaRusso and shares about season four of the Emmy-nominated series. In Hot Topics, Joy Behar, Sara Haines, Sunny Hostin, and Ana Navarro share how the new COVID-19 variant impacted their holidays and the reason behind moderator Whoopi Goldberg’s absence this week.