Stigma surrounds two growing public health problems in the United States: substance use disorder and suicide. In this episode of “Mental Health in America,” Sheri Doyle, who leads Pew’s substance use prevention and treatment initiative, and Allison Corr, from Pew’s suicide risk reduction project, discuss the rise in these disorders. We also hear from Dr. Rahul Gupta, director of the Office of National Drug Control Policy, who explains how stigma limits access to treatment, and from Abby Coulter, who shares her personal journey to receive methadone treatment. And Dr. Kimberly Roaten, a clinical psychologist at Parkland Health in Dallas, describes how the hospital is expanding access to care through universal suicide screening.