Looming international tax changes will be a big setback for Ireland's relationship with multinationals. But how great is the danger? And, how can we adapt to these changes, while continuing to attract foreign direct investment and develop other parts of the economy?To discuss how this might play out, Cliff Taylor is joined by chief economist at Ibec Gerard Brady and Martina Lawless, associate research professor at the ESRI and member of the Irish Fiscal Advisory Council.Plus: Laura Slattery on some of the other big stories this week, including steep Sterling loses and the continuing controversy surrounding Ireland's new Central Bank governor Gabriel Makhlouf.

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