At least 19 people, including nine children, killed in a deadly five alarm fire that broke out in a high-rise apartment building in the Bronx. New York City Mayor Eric Adams called the fire "one of the worst in modern times in the city." More than 80 percent of ICU beds occupied nationwide fueled by the Omicron variant surge. This, as dozens of schools in Chicago and Philadelphia shift to remote learning due to COVID-related staffing shortages. A brutal cold front sweeping from the deep south to the Northeast. The U.S. and Russia begin diplomatic talks tomorrow focusing on the crisis in the Ukraine. And tennis star Novak Djokovic goes to court in Australia over his vaccination status.