In this special episode Kate asks a medium to discuss the unsolved mysteries of the disappearance of Jennifer Kesse, the death of actress Brittany Murphy, whether Amanda Knox was involved in the death of her Italian roommate Meredith Kercher, and what really happened on July 18, 1969 on Chappaquiddick Island. 

Jennifer Joyce Kesse lived in Orlando, Florida and has been missing since January 24, 2006. Her disappearance puzzled investigators and an aggressive search for her was conducted in the area surrounding her home. Shortly after her disappearance, her car was discovered a little over a mile from her home at a nearby apartment complex. No evidence was ever made known with regards to her, such as finger prints, DNA or cellphone location information from nearby towers. Captured footage from a nearby security camera showed an unidentified person parking Kesse's car before walking away. The case received widespread state and national press attention at the time of her disappearance.

Brittany Murphy was an American actress and singer. A native of Atlanta, Murphy moved to Los Angeles as a teenager and pursued a career in acting. Her breakthrough role was as Tai Frasier in Clueless (1995), followed by supporting roles in independent films such as Freeway (1996) and Bongwater (1998). In December 2009, Murphy died of pneumonia at the age of 32. 

Meredith Kercher was a British student on exchange from the University of Leeds who was murdered at the age of 21 in Perugia, Italy, on 1 November 2007. Kercher was found dead on the floor of her bedroom. By the time the bloodstained fingerprints at the scene were identified as belonging to Rudy Guede, police had charged Kercher's American flatmate, Amanda Knox, and Knox's Italian boyfriend, Raffaele Sollecito. The subsequent prosecutions of Knox and Sollecito received international publicity. 

The Chappaquiddick incident was a single-vehicle car accident that occurred on Chappaquiddick Island, Massachusetts, on Friday, July 18, 1969. The late night accident was caused by Senator Ted Kennedy’s negligence, and resulted in the death of his 28-year-old passenger, Mary Jo Kopechne, who was trapped inside the vehicle.

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