Simpson's paradox is the data science equivalent of looking through one eye and seeing a very clear trend, and then looking through the other eye and seeing the very clear opposite trend. In one case, you see a trend one way in a group, but then breaking the group into subgroups gives the exact opposite trend. Confused? Scratching your head? Welcome to the tricky world of ecological inference.
Relevant links:
https://gking.harvard.edu/files/gking/files/part1.pdfgreat-example-of-simpsons-paradox.html">http://blog.revolutionanalytics.com/2013/07/a-great-example-of-simpsons-paradox.html