Dr. Birx, former Response Coordinator during the Trump administration of the White House Covid-19 Task Force, served also as the Global AIDS Coordinator and Special Representative for Global Health Diplomacy between April 2014 and January 2021. She joined us for an extended conversation on the accelerating changes surrounding us – the Delta variant surge, new discoveries regarding breakthrough infections among the vaccinated, continued vaccine hesitancy, and refusal that has prompted the declaration of “a pandemic of the unvaccinated.” As we speak, newly revised policies on masks and vaccinations are getting unveiled. What to make of this new phase, and where is it heading? We’ll need far higher testing and genomic sequencing, intensified local engagement, a big push on accelerating therapies, and thinking ahead on what the future mix of vaccines will look like.  Dr. Deborah Birx is a Senior Fellow at the George W. Bush Presidential Center