With all eyes on Conor McGregor and his UFC 246 battle with Cowboy Cerrone in Las Vegas, Ariel opens the show by explaining why he's so excited about this card. The show's first guest, UFC bantamweight Dominick Cruz talks about a conversation he shared with McGregor and the advice he has for him in facing off against Cerrone (23:39). Then, former UFC lightweight champion Eddie Alvarez tells Ariel about his plan to fight three times this year, which he hopes will ultimately land him a ONE Championship title fight (39:29). After that, UFC lightweight Anthony Pettis previews his Saturday matchup against Carlos Diego Ferreira before explaining how he's fallen back in love with "the process" of fighting during this camp (49:57). Plus, he tells a wild story about USADA. Then, in an exclusive interview, the man they call "Notorious" sits down with Ariel to discuss his newfound outlook on life, his confidence heading into this fight, the camaraderie he shares with his team, the role of his two children in his life, how he's managed to block out all of the criticism he's received, why he's chosen to fight Cerrone at 170 lbs., his questionable decision-making before the Khabib Nurmagomedov bout and how he hopes to rectify it by fighting him again, his relationship with life guru Tony Robbins, how much money he'll make off the Cerrone fight and much more (1:05:28). After that, 15 different celebrities weigh in with their UFC 246 picks, with predictions coming from the NBA's Kristaps Porzingis, WWE's Becky Lynch, actor Mario Lopez and many more (1:58:45). Owen Roddy, McGregor's striking coach, then discusses the holes in Cerrone's game and McGregor's readiness for the fight (2:05:58). Next, UFC flyweight Roxanne Modafferi, who fights Maycee Barber this weekend, talks about her social media exchanges with Barber and how she envisions Saturday night will unfold (2:24:34). Lastly, SBG Ireland's John Kavanagh makes his return to the show to candidly discuss how McGregor got his motivation back, why the Irishman needs to fight to stay grounded and out of trouble, if he thinks McGregor could fight Justin Gaethje next, and the last time he remembers seeing McGregor this focused and happy (2:35:32).