For a few brief moments this summer, in places where the vaccination rate was high, we could imagine life after COVID-19: restaurants and theatres were filling up, gatherings of all kinds were taking place, and many businesses were planning to return to their offices after Labor Day. Then the story changed, as the highly contagious Delta variant began sweeping the nation. Atul Gawande, a professor of medicine and an internationally recognized expert on public health, tells David Remnick that the Delta surge has also caused a vaccination surge, which is promising. They discuss the idea of booster shots and the possibility of a future variant that would resist the vaccine and cause more severe breakthrough infections. The Lambda variant, Gawande says, has already reached the U.S., but little is known yet about how it responds to the vaccines in use here. Plus, forget the big white tent and the plate of rubber chicken: the real New York style is a City Hall wedding, complete with metal detectors. Vinson Cunningham tells us what it’s all about.

(Gawande has been nominated by President Biden to lead global health development, including COVID-19 efforts, for the United States Agency for International Development. The appointment awaits confirmation in the Senate.)