This week on Supercharged we're finishing up our two-part healthcare special with a discussion about chronic pain, how pharmaceutical and illicit drugs function (or don't), and how your genetics plays into it all.

Links for this episode:

• Table of Pharmacogenomic Biomarkers in Drug LabelingPharmacogenomics can play an important role in identifying responders and non-responders to medications, avoiding adverse events, and optimizing drug dose. Drug labeling may contain information on genomic biomarkers and can describe.
• Pharmacogenetic biomarkers for predicting drug responseDrug response shows significant interpatient variability and evidence that genetics influences outcome of drug therapy has been known for more than five decades. However, the translation of this knowledge to clinical practice remains slow. Using examples from clinical practice six considerations about the implementation of pharmacogenetics (PGx) into routine care are discussed: the need for PGx biomarkers; the sources of genetic variability in drug response; the amount of variability explained by PGx; whether PGx test results are actionable; the level of evidence needed for implementation of PGx and the sources of information regarding interpretation of PGx data.
• ErowidA site that documents drug use, especially psychoactives. Go here and read the bad experiences if you need to scare yourself out of using pretty much any drug recreationally or in a dosage higher than prescribed.

No sponsor this week, so eat your vegetables!