Podknife - 184: CRISPR-Cas immune systems by This Week in Microbiology

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184: CRISPR-Cas immune systems

Podcast |: This Week in Microbiology
Publisher |: American Society for Microbiology
Media Type |: audio
Podknife tags |: Health,; Science & Medicine
Categories Via RSS |: Life Sciences,; Science
Publication Date |: Sep 07, 2018
Episode Duration |: 01:26:09

Sam Sternberg discusses his work on exploring and exploiting CRISPR-Cas immune systems, beginning as a graduate student with Jennifer Doudna, at a biotech start-up, and in his laboratory at Columbia University.

Host: Vincent Racaniello

Guest: Sam Sternberg

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Links for this episode

Sternberg Laboratory at Columbia
Mechanism of substrate selection by Cas9 (RNA)
DNA interrogation by Cas9 (Nature)
Conformational control of DNA target cleavage by Cas9 (Nature)
A Crack in Creation by Doudna and Sternberg
What if we could rewrite the human genome? (YouTube)
Sam Sternberg

Music used on TWiM is composed and performed by Ronald Jenkees and used with permission.

Send your microbiology questions and comments to twim@microbe.tv

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